Efficacy of Ketamine in the Treatment of Substance Use Disorders: A Systematic Review.
Frontiers in Psychiatry 2018 Jennifer L Jones, Camilo F Mateus, Robert J Malcolm et al.
Background: Despite advances in behavioral and pharmacotherapy interventions, substance use disorders (SUDs) are frequently refractory to treatment. Glutamatergic dysregulation has received increasing attention as one common neuropathology across multiple substances of abuse. Ketamine is a potent N-methyl-D-aspartate (NMDA) glutamatergic receptor antagonist which has been found to be effective...
DOI: 10.3389/fpsyt.2018.00277 (opens in new tab)
Full text (opens in new tab)
Addiction
Ketamine
Abstinence
Glutamate
+1