Timm Rosburg

Potential Mechanisms for the Ketamine-Induced Reduction of P3b Amplitudes.

Frontiers in Behavioral Neuroscience 2018 Timm Rosburg, André Schmidt

In specific dosages, the N-methyl-D-aspartate receptor (NMDA) antagonist ketamine can be used to model transient psychotic symptoms in healthy individuals that resemble those of schizophrenia. Ketamine administration also temporarily impairs cognitive functions, which can be studied by event-related potentials (ERPs). ERPs also allow dissecting what stages of information processing are affected...