Joseph A Dimicco

2 papers in the library · publishing 2008-2013

Papers

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Independent of 5-HT1A receptors, neurons in the paraventricular hypothalamus mediate ACTH responses from MDMA.

Neuroscience Letters October 25, 2013 Dmitry V Zaretsky, Maria V Zaretskaia, Joseph A Dimicco et al.

Acute and chronic complications from the substituted amphetamine 3,4-methylenedioxymethamphetamine (MDMA) are linked to activation of the hypothalamic-pituitary-adrenal (HPA) axis. How MDMA activates the HPA axis is not known. HPA responses to stress are known to be mediated through the paraventricular (PVH) hypothalamus and to involve serotonin-1a (5-HT1A) receptors. We sought to determine if...

DOI: 10.1016/j.neulet.2013.07.053 Full text MDMA 3,4-methylenedioxymethamphetamine 5-ht1a Acth +11

Microinjection of muscimol into the dorsomedial hypothalamus suppresses MDMA-evoked sympathetic and behavioral responses.

Brain Research August 21, 2008 Daniel E. Rusyniak, Maria V Zaretskaia, Dmitry V Zaretsky et al.

When given systemically to rats and humans, the drug of abuse 3,4 methylenedioxymethamphetamine (ecstasy, MDMA) elicits hyperthermia, hyperactivity, tachycardia, and hypertension. Chemically stimulating the dorsomedial hypothalamus (DMH), a brain region known to be involved in thermoregulation and in stress responses, causes similar effects. We therefore tested the hypothesis that neuronal...

DOI: 10.1016/j.brainres.2008.06.011 Full text