P Heckman

Memory and mood during MDMA intoxication, with and without memantine pretreatment.

Neuropharmacology December 2014 E B De Sousa Fernandes Perna, E L Theunissen, K P C Kuypers et al.

Previous studies have shown that single doses of MDMA can affect mood and impair memory in humans. The neuropharmacological mechanisms involved in MDMA-induced memory impairment are not clear. Memantine, an NMDA and alpha 7 nicotinic acetylcholine (ACh) receptor antagonist, was able to reverse MDMA-induced memory impairment in rats. This study investigated whether treatment with memantine can...