Downregulation of the Vitamin D Receptor Regulated Gene Set in the Hippocampus After MDMA Treatment.
Frontiers in Pharmacology 2018 Peter Petschner, Noemi Balogh, Csaba Ádori et al.
The active ingredient of ecstasy, ±3,4-methylenedioxymethamphetamine (MDMA), in addition to its initial reinforcing effects, induces selective and non-selective brain damage. Evidences suggest that the hippocampus (HC), a central region for cognition, may be especially vulnerable to impairments on the long-run, nevertheless, transcription factors that may precede and regulate such chronic...
DOI: 10.3389/fphar.2018.01373 (opens in new tab)
Full text (opens in new tab)
Ecstasy
Gene expression
Hippocampus
Long-term potentiation
+2