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Yusuke Katanuma

1 paper in the library · publishing 2014

Papers

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Phencyclidine rapidly decreases neuronal mRNA of brain-derived neurotrophic factor.

Synapse June 2014 Yusuke Katanuma, Tadahiro Numakawa, Naoki Adachi et al.

Downregulation of brain-derived neurotrophic factor (BDNF), a member of neurotrophin family, has been implicated in psychiatric diseases including schizophrenia. However, detailed mechanisms of its reduction in patients with schizophrenia remain unclear. Here, using cultured cortical neurons, we monitored BDNF mRNA levels following acute application of phencyclidine [PCP; an...

DOI: 10.1002/syn.21735 Full text Bdnf Nmda receptor Phencyclidine Schizophrenia