(R)-ketamine attenuates neurodevelopmental disease-related phenotypes in a mouse model of maternal immune activation.
European Archives of Psychiatry and Clinical Neuroscience October 2023 Elifrances Galdino de Oliveira, Diógenes Afonso De Lima, José Carlos Da Silva Júnior et al.
Infections during pregnancy are associated with an increased risk of neuropsychiatric disorders with developmental etiologies, such as schizophrenia and autism spectrum disorders (ASD). Studies have shown that the animal model of maternal immune activation (MIA) reproduces a wide range of phenotypes relevant to the study of neurodevelopmental disorders. Emerging evidence shows that (R)-ketamine...
DOI: 10.1007/s00406-023-01629-3 (opens in new tab)
Full text (opens in new tab)
R-ketamine
Emotional behavior
Inflammation
Maternal immune activation
+2