Effects of esketamine and fluoxetine on depression-like behaviors in chronic variable stress: a role of plasma inflammatory factors.
Frontiers in Psychiatry 2024 Haixia Chen, Xinxin Zhao, Xinxu Ma et al. 9 citations
Mounting evidence has identified the rapid and sustained antidepressive and anxiolytic-like effects of esketamine. However, the underlying mechanism of this no-monoamine target rapid-onset antidepressant is still underexplored. Immune-inflammatory pathways and cell-mediated immune activation, mainly including inflammatory cytokines in plasma, play a pivotal role in the pathogenesis of major...
DOI: 10.3389/fpsyt.2024.1388946 (opens in new tab)
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Esketamine
Major depressive disorder
Chronic variable stress
Fluoxetine
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