Ashley Blanchette

Cannabinoid modulation of corticolimbic activation to threat in trauma-exposed adults: a preliminary study.

Psychopharmacology June 2020 Christine A Rabinak, Ashley Blanchette, Nicole L Zabik et al.

Excessive fear and anxiety, coupled with corticolimbic dysfunction, are core features of stress- and trauma-related psychopathology, such as posttraumatic stress disorder (PTSD). Interestingly, low doses of ∆9-tetrahydrocannabinol (THC) can produce anxiolytic effects, reduce threat-related amygdala activation, and enhance functional coupling between the amygdala and medial prefrontal cortex and...