The efficacy and safety of MDMA-assisted psychotherapy for treatment of posttraumatic stress disorder: A systematic review and meta-analysis from randomized controlled trials.
Psychiatry Research September 1, 2024 Jianhua Yang, Ni Wang, Wulin Luo et al. 14 citations
MDMA-assisted psychotherapy reduces PTSD symptoms more than placebo or active controls, based on seven randomized controlled trials. The therapy lowered scores on the Clinician-Administered PTSD Scale from baseline. However, MDMA causes adverse events such as muscle tightness, nausea, and decreased appetite. Side effects and abuse potential seriously hinder its clinical use.