Mindfulness-based Real-time fMRI Neurofeedback: A Randomized Controlled Trial to Optimize Dosing for Depressed Adolescents (Study Protocol)
September 23, 2023 Paul Alexander Bloom, David Pagliaccio, Jiahe Zhang et al. preprint
Adolescence is characterized by a heightened vulnerability for Major Depressive Disorder (MDD) onset, and currently, treatments are only effective for roughly half of adolescents with MDD. Accordingly, novel interventions are urgently needed. This study aims to establish mindfulness-based real-time fMRI neurofeedback (mbNF) as a non-invasive approach to downregulate the default mode network...