Gijs H J Roelandt

2 papers in the library · 14 citations · publishing 2024-2025

Papers

Sort Most recent Most cited

The Ketamine Trial for Acute Suicidality (KETA): Study Protocol of a Double-Blind Randomized Placebo-Controlled Superiority Trial on Intranasal Racemic Ketamine Compared to the Active Placebo Intranasal Midazolam as Treatment for Acute Suicidality.

International Journal of Methods in Psychiatric Research December 1, 2025 Jurriaan F M Strous, Gijs H J Roelandt, Jens H van Dalfsen et al. 1 citation

Suicidality is a transdiagnostic entity in patients with and without psychiatric disorders. Ketamine is a novel treatment for treatment-resistant depression with favorable effects on related suicidality in this population. Little is known about the effects of ketamine on suicidality as a distinct phenomenon. To assess whether a dose of 75 mg intranasal (IN) ketamine reduces acute suicidality...

DOI: 10.1002/mpr.70044 Full text Randomized controlled trial Ketamine for suicidality Rapid intervention

Shared effects of electroconvulsive shocks and ketamine on neuroplasticity: A systematic review of animal models of depression.

Neuroscience & Biobehavioral Reviews September 1, 2024 Jesca E. de Jager, Rutger Boesjes, Gijs H J Roelandt et al. 13 citations

Electroconvulsive shocks (ECS) and ketamine are antidepressant treatments with a relatively fast onset of therapeutic effects compared to conventional medication and psychotherapy. While the exact neurobiological mechanisms underlying the antidepressant response of ECS and ketamine are unknown, both interventions are associated with neuroplasticity. Restoration of neuroplasticity may be a...

DOI: 10.1016/j.neubiorev.2024.105796 Full text Ketamine Neurogenesis Electroconvulsive shocks Ltp/ltd +7