Haloperidol prevents ketamine- and phencyclidine-induced HSP70 protein expression but not microglial activation.
Experimental Neurology February 1, 1996 Riitta Näkki, J Nickolenko, J Chang et al.
Noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonists, inclu ding ketamine and phencyclidine (PCP), produce abnormal intracellular vacuoles in posterior cingulate and retrosplenial cortical neurons in the rat. Ketamine also induces 70-kDa heat shock protein (HSP70) expression in pyramidal neurons in the posterior cingulate and retrosplenial cortex and, as shown by this study,...
DOI: 10.1006/exnr.1996.0022 (opens in new tab)
Ketamine
Microglia
Animals
Rats, sprague-dawley
+6