Comparing the adverse effects of ketamine and esketamine between genders using FAERS data.
Frontiers in Pharmacology 2024 Xinxia Yang, Dongdong Chen 10 citations
Ketamine was developed as an anesthetic. Esketamine is the isolated S-enantiomer of racemic ketamine. They provide new avenues for the treatment of depression, especially treatment-resistant depression. Considering differences in the pharmacokinetics and hormonal status of ketamine in patients of different genders, sex-based differences in esketamine adverse drug events (ADE) may also be...
DOI: 10.3389/fphar.2024.1329436 (opens in new tab)
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Esketamine
Adverse drug events
Gender difference
Signal mining
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