Wenjuan Yang

The HIV antiretroviral drug efavirenz has LSD-like properties.

Neuropsychopharmacology May 24, 2013 Michael B. Gatch, Alexey Kozlenkov, Ren-Qi Huang et al.

Anecdotal reports have surfaced concerning misuse of the HIV antiretroviral medication efavirenz ((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one) by HIV patients and non-infected teens who crush the pills and smoke the powder for its psychoactive effects. Molecular profiling of the receptor pharmacology of efavirenz pinpointed interactions with...