Frequent Δ9- tetrahydrocannabinol exposure during adolescence impairs sociability in adult mice exposed to an aversive painful stimulus.
European Neuropsychopharmacology December 2021 Alex Mabou Tagne, Yannick Fotio, Zachary Alan Springs et al.
Early-life exposure to Δ9-tetrahydrocannabinol (Δ9-THC), the intoxicating constituent of cannabis, may produce enduring neurochemical changes in brain structures involved in the regulation of sociality but it is still unclear how such changes influence social behavior later in life. In the present study, we exposed male mice to moderate daily doses of Δ9-THC (5 mg/kg, intraperitoneal) during...
DOI: 10.1016/j.euroneuro.2021.07.007 (opens in new tab)
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THC
Adolescence
Formalin
Social behavior
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