Nicotine and modafinil combination protects against the neurotoxicity induced by 3,4-Methylenedioxymethamphetamine in hippocampal neurons of male rats.
Journal of chemical neuroanatomy October 2021 Golshad Kowsari, Soraya Mehrabi, Sara Soleimani Asl et al.
MDMA (3,4-Methylenedioxymethamphetamine) is a common recreational drug of abuse which causes neurodegeneration. Nicotine and modafinil provide antioxidant and neuroprotective properties and may be beneficial in the management of MDMA-induced neurotoxicity. The purpose of this study was to characterize how acute and chronic administration of nicotine and/or modafinil exert protective effects...
DOI: 10.1016/j.jchemneu.2021.101986 (opens in new tab)
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MDMA
Apoptosis
Modafinil
Nicotine
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