Chronic use of cannabis might impair sensory error processing in the cerebellum through endocannabinoid dysregulation.
Addictive Behaviors August 2022 Adrián F Amil, Belén Rubio Ballester, Martina Maier et al.
Chronic use of cannabis leads to both motor deficits and the downregulation of CB1 receptors (CB1R) in the cerebellum. In turn, cerebellar damage is often related to impairments in motor learning and control. Further, a recent motor learning task that measures cerebellar-dependent adaptation has been shown to distinguish well between healthy subjects and chronic cannabis users. Thus, the...
DOI: 10.1016/j.addbeh.2022.107297 (opens in new tab)
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Cerebellum
Chronic cannabis use
Endocannabinoid system
Error processing
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