Fast-acting antidepressant-like effects of ketamine in aged male rats.
Pharmacological Reports October 1, 2024 Elena Hernández-Hernández, Sandra Ledesma-Corvi, Jordi Jornet-Plaza et al. 8 citations
The aging process causes anatomical and physiological changes that predispose to the development of late-life depression while reduces the efficacy of classical antidepressants. Novel fast-acting antidepressants such as ketamine might be good candidates to be explored in the context of aging, especially given the lack of previous research on its efficacy for this age period. Thus, the aim of...
DOI: 10.1007/s43440-024-00636-y (opens in new tab)
Full text (opens in new tab)
Aging
Bdnf
Fast-acting antidepressant
Ketamine therapy
+4