Jelena Petrović

2 papers in the library · 3 citations · publishing 2016-2025

Papers

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Single subanesthetic dose of ketamine exerts antioxidant and antidepressive-like effect in ACTH-induced preclinical model of depression.

Molecular and cellular neurosciences June 1, 2025 Ana Ivanović, Jelena Petrović, Dušanka Stanić et al. 3 citations

Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis and oxidative stress represent important mechanisms that have been implicated in etiopathology of depression. Although first antidepressants were introduced in clinical practice more than six decades ago, approximately 30 % of patients with a diagnosis of depression show treatment resistance. A noncompetitive N-methyl-d-aspartate...

DOI: 10.1016/j.mcn.2025.104006 Full text Major depressive disorder Acth Dna Oxidative stress +5

Molecular Mechanism and Clinical Relevance of Ketamine as Rapid-Acting Antidepressant.

Drug Development Research November 2016 Vesna Pešić, Jelena Petrović, Marin M Jukić

Preclinical Research The emergence of rapid-acting antidepressants such as ketamine has motivated studies aiming to reveal the molecular mechanism of the ketamine antidepressant effect and to enable the clinical application of rapid-acting antidepressants. Here, we provide an overview of studies addressing the antidepressant effects of ketamine in depressed patients and animal models of...

DOI: 10.1002/ddr.21335 Full text Ketamine Treatment-resistant depression Major depression Rapid-acting antidepressant