Prenatal cannabinoid exposure alters excitation-inhibition balance through glutamate and GABA receptor-mediated signaling.
The Journal of biological chemistry July 2026 Priyanka D Pinky, Warren D Smith, Miles T Wiley et al.
The growing perception that marijuana is safe during pregnancy has led to a marked increase in prenatal cannabis use, raising concerns about its long-term effects on brain development and cognition. This study investigated the consequences of prenatal delta-9-tetrahydrocannabinol (THC) exposure on hippocampal circuit function, synaptic plasticity, and memory in adolescent offspring using a...