Ketamine and esketamine are increasingly used to manage treatment-resistant depression and have also been shown to reduce symptoms of posttraumatic stress disorder (PTSD). Little is known about how common comorbidities in the veteran population, such as traumatic brain injury (TBI) or obstructive sleep apnea (OSA), may influence ketamine and esketamine treatment outcomes. In this retrospective...
Nightmares and insomnia commonly co-occur with Posttraumatic Stress Disorder (PTSD), with 70% to 91% of individuals with PTSD reporting chronic nightmares and insomnia. Evidence suggests that even gold standard treatments for PTSD (such as Prolonged Exposure, PE) and insomnia (CBT-I) individually may not fully resolve nightmares. Our study presents secondary analyses of a randomized controlled...