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Gwenaëlle Le Pen

2 papers in the library · 146 citations · publishing 2014-2025

Papers

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Lifelong dietary Omega-3, -6, and -9 ratios shape adult behavior and response to adolescent THC exposure in rats.

Pharmacology, Biochemistry, and Behavior November 2025 Ariel Frajerman, Aude Marzo, Boris Chaumette et al.

Alterations in membrane lipids are well established in schizophrenia, and diet could be an accessible, modifiable etiological factor. We examined the influence of Polyunsaturated fatty acids (PUFAs) intake throughout the lifespan on behaviour in adult rats. We further explored a possible interaction with adolescent exposure to delta-9-tetrahydrocannabinol (THC), the lipidic psychoactive...

DOI: 10.1016/j.pbb.2025.174086 (opens in new tab) Full text (opens in new tab) Brain maturation Cannabinoids Omega-3 Omega-6 +2

Long-term consequences of adolescent cannabinoid exposure in adult psychopathology

Frontiers in Neuroscience November 10, 2014 Justine Renard, Marie-Odile Krebs, Gwenaëlle Le Pen et al. 146 citations

Marijuana is the most widely used illicit drug among adolescents and young adults. Unique cognitive, emotional, and social changes occur during this critical period of development from childhood into adulthood. The adolescent brain is in a state of transition and differs from the adult brain with respect to both anatomy (e.g., neuronal connections and morphology) and neurochemistry (e.g.,...