Activity in the dorsal hippocampus-mPFC circuit modulates stress-coping strategies during inescapable stress.
Experimental & molecular medicine September 1, 2024 Sang Ho Yoon, Woo Seok Song, Geehoon Chung et al. 14 citations
Anatomical connectivity and lesion-deficit studies have shown that the dorsal and ventral hippocampi contribute to cognitive and emotional processes, respectively. However, the role of the dorsal hippocampus (dHP) in emotional or stress-related behaviors remains unclear. Here, we showed that neuronal activity in the dHP affects stress-coping behaviors in mice via excitatory projections to the...
DOI: 10.1038/s12276-024-01294-z (opens in new tab)
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Stress-response
Brain-circuits
Mental-health
Antidepressants