Examining Insula–Default Mode Network Functional Connectivity and Its Relationship with Heart Rate Variability
Brain Science 2025 Marlene Nogueira, Juliana da Silva Magalhães, Adriana Sampaio et al.
Background: The Default Mode Network (DMN) is involved in self-referential and emotional processes, while the insula integrates emotional and interoceptive signals. Functional connectivity between the insula and the DMN is proposed to enhance these processes by linking internal bodily states with self-referential thoughts and emotional regulation. Heart Rate Variability (HRV), a measure of...