The role of sex in the association between cannabis use disorder and resting-state functional connectivity.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology May 2025 Janna Cousijn, Yara J Toenders, Anne Marije Kaag et al.
While Cannabis use disorder (CUD) is twice as prevalent in males, females transition more quickly from heavy use to CUD and experience more severe withdrawal. These clinically relevant sex differences contrast the lack of knowledge about the underlying brain mechanisms. This study investigated the relationship between CUD and resting-state functional brain connectivity (RSFC), assessing...