Neurophysiological connectomic signatures of consciousness during propofol-induced general anesthesia.
Cell reports. Medicine February 17, 2026 Yuqin Li, Xiaoxiao Chen, Hui Zheng et al.
General anesthesia induces reversible changes in consciousness through cortical activity and connectivity alterations, yet the functional connectome dynamics underlying propofol-induced unconsciousness remains unclear. We analyze high-density 128-channel electroencephalogram (EEG) from 31 surgical patients using source localization to identify neurobiological connectome signatures of propofol...