B-285 Whippits, Nangs, Balloons, and Crackers: Functional Inactivation of Vitamin B12
Clinical Chemistry October 1, 2025 P. Gyawali, C. Suthaharen, J. Chung
Nitrous oxide (N2O or laughing gas) has been used for many legitimate medical, commercial, and industrial purposes. Recreational use of N2O via ‘Whippit’ or ‘nangs’ is on the rise. Prolonged use of N2O can very rapidly cause functional inactivation of Vitamin B12, leading to disabling neuropsychiatric sequelae. Early diagnosis and vitamin B12 replacement is critical to reducing residual...