Brain structural changes underlying clinical symptom improvement following fast-acting treatments in treatment resistant depression.
Journal of Affective Disorders January 15, 2025 Zhiliang Long, Jiao Li, Marco Marino 7 citations
Electroconvulsive therapy (ECT), ketamine infusion (KI), and total sleep deprivation (TSD) are effective and fast in treating patients with treatment-resistant depression (TRD). However, it remains unclear whether the three treatments have the same effect on clinical symptom improvement and have common brain structural mechanisms. The current study included 127 TRD patients and 37 healthy...