661. A SINGLE DOSE OF LYSERGIC ACID DIETHYLAMIDE (LSD) REDUCES ALCOHOL CONSUMPTION AND REVERTS DOPAMINERGIC (DA) DISFUNCTION IN MALE MICE
International Journal of Neuropsychopharmacology August 18, 2025 I Esquivel, I Soliman, F Ruto et al.
Abstract Background Alcohol use disorder (AUD) presents significant health and societal issues. The disorder is characterized by locomotor impairments and disruption of the dopaminergic neurotransmission in the ventral tegmental area (VTA). Current AUD treatments are limited, necessitating the exploration of novel drugs. The potential therapeutic use of psychedelics, particularly lysergic acid...