INTEGRATION OF PHARMACOLOGICAL THERAPIES WITH MULTIMODAL NON-PHARMACOLOGICAL APPROACHES IN HEART FAILURE
Revista de Estudos Interdisciplinares August 6, 2026 Helena Victor Leite Panadés, Isadora Queiroz Graça, Maria Fernanda Vasconcelos Mascarenhas Clementino et al.
Introduction: Treatment-resistant depression (TRD) is characterized by the persistence of depressive symptoms following at least two adequate therapeutic trials with distinct classes of antidepressants. Given the limited efficacy of the traditional monoaminergic model and the high socioeconomic and functional burden of the disease, interventions with rapid mechanisms of action have become...