MK-801 and related compounds in monkeys: discriminative stimulus effects and effects on a conditional discrimination.
Journal of Pharmacology and Experimental Therapeutics May 1, 1991 C. France, J. Moerschbaecher, James H Woods
MK-801 [(+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5, 10-imine maleate] and related compounds were studied in monkeys discriminating between 0.032 mg/kg of (+)-MK-801 and saline and in a separate group of monkeys responding under a multiple schedule of repeated acquisition and performance of conditional discriminations. In the drug discrimination study, small doses of (+)-MK-801...