Gestational exposure to phencyclidine (PCP) in rats decreases PCP binding sites in term fetal brain
International Journal of Developmental Neuroscience 1988 S. F. Ali, G. Ahmad, W. Slikker et al.
AbstractPregnant Sprague‐Dawley rats were treated with 5 mg/kg body weight of phencyclidine (PCP) injected at 1 ml/kg subcutaneously on three consecutive days at four different stages of gestation. Within 10–30 min after treatment, dams showed some lack of motor coordination and became lethargic. On gestational day 21, all rats were killed by decapitation and brains were dissected and stored...