Effects of risperidone on phencyclidine-induced behaviors: comparison with haloperidol and ritanserin.
Japanese journal of pharmacology October 1994 K Kitaichi, K Yamada, T Hasegawa et al.
In this study, we investigated whether risperidone, a serotonin-S2A (5-HT2A)/dopamine-D2 (D2)-receptor antagonist, inhibits phencyclidine (PCP)-induced stereotyped behaviors in comparison with haloperidol and ritanserin. Moreover, we also attempted to investigate the effects of these antipsychotics on the contents of dopamine, serotonin (5-HT) and their metabolites in rat striatum and frontal...