Discriminative stimulus properties and brain distribution of phencyclidine in rats following administration by injection and smoke inhalation.
Pharmacology, biochemistry, and behavior October 1985 W D Wessinger, B R Martin, R L Balster
Four male Sprague-Dawley rats were trained to discriminate IP injections of 3.0 mg/kg phencyclidine (PCP) from saline under a 2-lever fixed-ratio 32 schedule of food presentation. After reliable discriminative control of lever choice was established, other doses of injected PCP were tested resulting in dose-dependent increases in PCP-lever selection and dose-dependent decreases in rates of...