Inhibition of phrenic and sympathetic vasomotor neurons in cats by the serotonin analog 5-methoxy-N,N-dimethyltryptamine.
Journal of Pharmacology and Experimental Therapeutics March 1, 1982 P. Lalley
5-Methoxy-N,N-dimethyltryptamine (20-200 microgram/kg) inhibits phrenic and sympathetic neural discharges and depresses blood pressure. The effects occur within seconds after injection. Complete recovery occurs, on the average, after 20 min. The inhibition of phrenic nerve discharges is prevented during hypercapnia and hyperthermia and reversed during 50 Hz electrical stimulation of the carotid...