Ketamine effects on somatosensory cortical single neurons and on behavior in rats.
Anesthesia and analgesia June 1990 I M Patel, J K Chapin
The neurophysiological effects of ketamine were studied at the single-neuron level in the somatosensory cortex of unanesthetized rats behaving in a treadmill movement paradigm. Chronically implanted 25-microns microwire electrodes were used to record spontaneous discharge, sensory responses, and sensorimotor-correlated activity of single neurons before and after ketamine administration....