LACK OF ENHANCEMENT OF DIMETHYLTRYPTAMINE FORMATION IN RAT BRAIN AND RABBIT LUNG IN VIVO BY METHIONINE OR S‐ADENOSYLMETHIONINE
Journal of Neurochemistry October 1, 1978 Giorgio Stramentinoli, Ross J. Baldessarini
Abstract In vivo conversion of intracisternally administered [14C]tryptamine to [14C]N,N‐dimethyl‐tryptamine (DMT) in rat brain, even in the presence of an excess of substrate and methyl donor appeared to be insignificant, although enzymatically synthesized [14C]DMT was recovered readily after intracranial injection. Authenticity of [14C]DMT was demonstrated by cocrystallization with authentic...