Genetic Pathways Point to the Biology Underlying the Association Between Cannabis Use Disorder and Psychosis
Biological Psychiatry Global Open Science May 13, 2026 I. Austin-Zimmerman, Qiang Li, E. Johnson et al.
Background Cannabis use is associated with increased risk of psychotic disorders, but the underlying biological mechanisms remain unclear. We used genetic data to investigate the molecular pathways contributing to the association between cannabis use disorder (CUD) and psychosis. Methods We conducted a cross-disorder meta-analysis of genome-wide association studies (GWASs) on schizophrenia and...