530. Detecting neuroplastic effects induced by ketamine and classic psychedelics in healthy human subjects
International Journal of Neuropsychopharmacology September 9, 2026 C Agnorelli, J Peill, D Kurtin et al.
Abstract Background Clinical studies have shown that ketamine and classic psychedelics can produce robust and rapid antidepressant effects after a single or a few administrations. However, the neurobiological mechanisms driving these long-lasting changes remain unclear. A leading framework proposes that both drug classes induce sustained increases in neuroplasticity, potentially reshaping...