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M Clarke

1 paper in the library · publishing 2026

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530. Detecting neuroplastic effects induced by ketamine and classic psychedelics in healthy human subjects

The International Journal of Neuropsychopharmacology September 9, 2026 Claudio Agnorelli, Joseph Peill, Danielle Kurtin et al.

Abstract Background Clinical studies have shown that ketamine and classic psychedelics can produce robust and rapid antidepressant effects after a single or a few administrations. However, the neurobiological mechanisms driving these long-lasting changes remain unclear. A leading framework proposes that both drug classes induce sustained increases in neuroplasticity, potentially reshaping...