Zenodo (CERN European Organization for Nuclear Research)
September 13, 2026
Flávio Marco Rego da Silva
preprint
The ratio R = E/|O_info| - spectral energy per unit of integrated informational structure - was proposed as a candidate outcome observable of the thermodynamics of consciousness: an energetic cost per nat of integration. We report its complete empirical genealogy across eight pre-registered studies in public datasets (Sleep-EDF, 153 nights, N=76/77; DOSE-I propofol, N=170; 62-channel ketamine,...
Zenodo (CERN European Organization for Nuclear Research)
September 7, 2026
Flávio Marco Rego da Silva
preprint
Rationale: Increased neural complexity under psychedelics is replicated, but the temporal structure carrying it — and the design choices that decide what a "complexity increase" means — remain contested: window-level reports treat correlated windows as independent; cross-dataset contrasts confound pharmacology with protocol. Objectives: To test, in public EEG datasets with pre-registered...
Zenodo (CERN European Organization for Nuclear Research)
September 7, 2026
Flávio Marco Rego da Silva
preprint
The hypothesis that consciousness corresponds to integrated information predicts that measures of integration computed over the whole physiological system co-vary with the level of consciousness. Sleep provides an expert-scored axis from wakefulness through deep non-rapid-eye-movement sleep to rapid-eye-movement sleep. In 153 polysomnographic nights from a public cohort (78 subjects; two...
Zenodo (CERN European Organization for Nuclear Research)
September 7, 2026
Flávio Marco Rego da Silva
preprint
Meditation research has measured isolated physiological channels for decades, but the set of peripheral signs has rarely been treated as a field — a totality whose inter-channel dependency structure is itself the observable. We tested whether a guided meditation session moves the integrated peripheral field, or only the individual signs, in the public WESAD dataset (15 subjects; within-subject...
Zenodo (CERN European Organization for Nuclear Research)
September 7, 2026
Flávio Marco Rego da Silva
preprint
Consciousness science routinely operationalizes theoretical constructs — integration, complexity, coupling, level — as measurable proxies, and then tests hypotheses about the constructs through the proxies. This chain is only as strong as its weakest translation. We present a post-execution proxy-fidelity audit framework, developed and applied across 18 consecutive research cycles of a...