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Keith Karcher

1 paper in the library · 9 citations · publishing 2024

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Effect of Esketamine Nasal Spray on Cognition in Patients With Treatment-Resistant Depression: Results From Four Phase 3 Studies.

The International Journal of Neuropsychopharmacology November 1, 2024 Randall L. Morrison, Jaskaran Singh, Ella Daly et al. 9 citations

While esketamine is effective in treatment-resistant depression (TRD), detailed information about the effect of esketamine on cognition is relatively scarce. This analysis assessed the effect of short-term (3 double-blind [DB] studies: DB1, DB2, and DB4) or long-term maintenance treatment (DB3) with esketamine nasal spray (ESK) compared with a placebo (PBO) combined with active-comparator, on...