Elevated impulsivity and impaired decision-making cognition in heavy users of MDMA (“Ecstasy”)
Psychopharmacology January 20, 2006 B. Quednow, K. Kühn, C. Hoppe et al.
RationaleIn animal studies, the common club drug 3,4-methylendioxymethamphetamine (MDMA, “Ecstasy”) consistently caused a prolonged loss of presynaptic serotonergic neurons, and evidence suggests that MDMA consumption may also affect the human serotonergic system. Serotonin (5-HT) has been implicated in the regulation of impulsivity and such executive functions as decision-making cognition. In...