Impaired Spatial Memory after Ketamine Administration in Chronic Low Doses
Current Neuropharmacology March 1, 2011 Carlos Venâncio, Ana Magalhães, Luís Antunes et al.
Ketamine is a noncompetitive antagonist of the NMDA-receptors, used as a dissociative anesthetic, presently included in the category of the psychoactive substances known as “club drugs”. Ketamine administration was associated with impaired working memory and increased psychopathological symptoms, but there is a lack of information regarding the effects of chronic sub-anesthetic doses. Adult...