K M O'Boyle

2 papers in the library · publishing 2001-2018

Papers

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Effects of a combination of 3,4-methylenedioxymeth amphetamine and caffeine on real time stimulated dopamine release in the rat striatum: Studies using fast cyclic voltammetry.

Journal of Neuroscience Methods April 15, 2018 J J O'Connor, K M O'Boyle, J P Lowry

It is well documented that caffeine exacerbates the hyperthermia associated with acute exposure to 3,4-methylenedioxymethamphetamine (MDMA) in rats. Previous reports have also indicated that MDMA-related enhancement of dopamine release is exacerbated in the presence of caffeine. In the present study we have examined whether the effects of MDMA on real-time stimulated dopamine release, in the...

DOI: 10.1016/j.jneumeth.2017.08.026 Full text MDMA Caffeine Cyclic voltammetry Rat striatum +1

Behavioural, hyperthermic and neurotoxic effects of 3,4-methylenedioxymethamphetamine analogues in the Wistar rat.

Progress in Neuro-Psychopharmacology and Biological Psychiatry April 2001 E D O'Loinsigh, G Boland, J P Kelly et al.

1. The ability of N-ethyl (MDEA) and N-butyl (MDBA) analogues of 3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy') to induce acute behavioural changes and increases in body temperature, and to cause serotonergic neurotoxicity, was assessed in young adult male Wistar rats. The in vitro ability of MDMA analogues to evoke presynaptic monoamine release from crude rat forebrain synaptosomal...

DOI: 10.1016/s0278-5846(00)00179-2 Full text