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Vardan T. Karamyan

1 paper in the library · 16 citations · publishing 2009

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In vitrostudies on metabolism of salvinorin A

Pharmaceutical Biology October 19, 2009 Lukasz Kutrzeba, Vardan T. Karamyan, Robert C. Speth et al. 16 citations

Microbial transformation of natural products is a well established model for mammalian metabolism. Salvinorin A, a diterpenoid isolated from the hallucinogenic mint Salvia divinorum Epling & Játiva-M (Lamiaceae), is a potent non-nitrogenous κ-opioid receptor agonist. The metabolism of salvinorin A has still not yet been well established. Thirty fungal species were screened for the ability to...