Ketamine-induced disruption of verbal self-monitoring linked to superior temporal activation.
Pharmacopsychiatry January 2011 J M Stone, K M Abel, M P G Allin et al.
Misattribution of distorted self-generated speech in patients with schizophrenia has been associated with increased lateral temporal activation. As a pharmacological model of schizophrenia, we tested whether ketamine would induce the same effects in healthy individuals. Participants were 8 healthy male volunteers who were naïve to ketamine (mean age: 28 years). Ketamine (0.23 mg/kg bolus...