The effects of the 3,4-methylenedioxymethamphetamine (Ecstasy) in some cerebral areas: role of the oxidative stress.
Drug metabolism letters April 2008 Sergio Franzese, Anna Capasso
The purpose of the present review is to examine the effect of the acute administration (20 mg/ Kg, i.p.) of the 3,4 methylenedioxymethamphetamine (MDMA) in different cerebral areas of rats to better understand the mechanism underlying the toxicity induced by cellular oxidative stress. For this purpose the biochemical parameters of the antioxidant non-enzymatic cellular defense system have been...