Rewarding effects of 3,4-methylenedioxymethamphetamine ("Ecstasy") in dominant and subordinate OF-1 mice in the place preference conditioning paradigm.
Progress in neuro-psychopharmacology & biological psychiatry January 30, 2007 G Rodriguez-Alarcón, J J Canales, A Salvador
We tested the ability of 3,4-methylenedioxymethamphetamine (MDMA) to induce conditioned place preference (CPP) in dominant and subordinate OF-1 mice subjected to cohabitation and repeated sessions of agonistic confrontation, as well as in non-confronted mice. We selected doses of MDMA (2, 6, 10 mg/kg) previously reported to induce CPP in mice and we measured expression of c-Fos evoked by the...